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AI models developed by Boston University researchers can accurately diagnose dementia by analyzing complex patient data, performing similarly to physicians. More individuals are surviving into old age globally thanks to improvements in public health over the last several decades. Dementia, notably A...

Distinct gut microbiota imbalances in DLB, compared to Parkinson’s, suggest new diagnostic tools and therapies targeting neuroinflammation and neuronal health. Dementia with Lewy bodies (DLB) is a common form of dementia that currently has no cure. Previous research has suggested that the gut microb...

A biomarker of norepinephrine deficiency in the heart may help to detect Lewy body diseases before symptoms appear. In a small study, researchers at the National Institutes of Health have found that positron emission tomography (PET) scans of the heart may identify people who will go on to develop P...

Research from UC Berkeley indicates that ongoing stress caused by protein aggregation is leading to the death of brain cells. Numerous neurodegenerative conditions, including Alzheimer’s and Parkinson’s, involve the buildup of protein clusters, known as aggregates, within the brain. This...

Protein aggregation underlies many neurodegenerative diseases affecting the brain, including Alzheimer’s and dementia. Scientists at the University of Copenhagen have created a new instrument to detect and analyze these small protein clusters. This breakthrough offers deeper insights into the ...

Research suggests that drugs for enlarged prostate, like terazosin and doxazosin, may also protect against dementia with Lewy bodies by enhancing brain cell energy production. A study of over 643,000 men showed that those on these drugs had a 40% lower risk of developing DLB, pointing to potential n...

Work could lead to the discovery of new therapeutic targets. For the first time, researchers have identified “molecular markers” linked to degeneration—detectable changes in cells and their gene-regulating networks—that are common across several types of dementia affecting different brai...

American actor Robin Williams had a neurodegenerative brain disease called dementia with Lewy bodies (DLB): a distressing disease, with symptoms in common with Alzheimer’s disease (AD) and Parkinson’s disease (PD). But unlike these two conditions, DLB also entails prominent mood and cogn...

Processed Meat Raises Dementia Risk; Unprocessed Red Meat May Reduce It Scientists from the University of Leeds’s Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent of one rasher of bacon, is associated...

Hydrogen sulfide disrupts potassium channels in brain cells, leading to overexcitation and damage—key traits in conditions like dementia and epilepsy. Targeting this gas may open new therapeutic paths. A potential treatment for dementia and epilepsy could look to reduce the amounts of a toxic gas in...

Declining kidney function significantly raises dementia risk, with up to 10% of cases potentially linked to chronic kidney disease. Older people with kidney disease have a higher risk of dementia, and the risk increases with the rate and stage of kidney function decline. That is according to a large...

Acoustical environments can prevent, reduce behavioral and psychological symptoms. Designing a soundscape to improve the quality of life for an individual is centered on putting their perception at the heart of the process. It becomes trickier for people who have diminished cognitive capacities. Dur...

Observational study adds to growing evidence that statin therapy is not associated with cognitive decline and dementia in older adults, but randomized trials are still needed. The use of statin therapy in adults 65 years old or older is not associated with incident dementia, mild cognitive impairmen...

PET scans show lipophilic statins may accelerate cognitive decline in vulnerable patients, linking them to early Alzheimer’s-related brain changes. In patients with mild cognitive impairment, taking lipophilic statins more than doubles their risk of developing dementia compared to those who do not t...

Good oral health, including dentures, may protect against cognitive decline. Tooth loss is a risk factor for cognitive impairment and dementia–and with each tooth lost, the risk of cognitive decline grows, according to a new analysis led by researchers at NYU Rory Meyers College of Nursing and...

Improving Air Quality May Reduce Dementia Risk Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today (July 26, 2021) at the Alzheimer’s Association International Conference® (AAIC®) 2021 in Denver and virtually. Previous...

New analysis shows a decrease in prevalence due to education countered by increase due to heart health risk factors. Positive trends in global education access are expected to decrease dementia prevalence worldwide by 6.2 million cases by the year 2050. Meanwhile, anticipated trends in smoking, high...

A UW study linked small increases in long-term PM2.5 exposure to a 16% higher risk of dementia. Using data from two large, long-running study projects in the Puget Sound region — one that began in the late 1970s measuring air pollution and another on risk factors for dementia that began in 1994 — Un...

Findings independent of age, sex, general health and lifestyle. Widespread pain is linked to a heightened risk of all types of dementia, including Alzheimer’s disease, and stroke, finds research published online in the journal Regional Anesthesia & Pain Medicine. And this association is ind...

Certain proteins might provide clues to underlying biological mechanisms, say researchers. People with mentally stimulating jobs have a lower risk of dementia in old age than those with non-stimulating jobs, according to a study published by The BMJ today (August 18, 2021).  One possible explan...

Beige fat protects the brain by reducing inflammation. Its absence triggers cognitive decline, while its presence boosts memory and brain health in mice. Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the in...

A large study at Karolinska Institutet in Sweden has found a link between ADHD and dementia across generations. The study, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, shows that parents and grandparents of individuals with ADHD were at higher...

Artificial intelligence could spot the early signs of dementia from a simple brain scan long before major symptoms appear – and in some cases before any symptoms appear – say Cambridge researchers. Dementias are characterized by the build-up of different types of protein in the brain, which damages ...

A new Rutgers study will examine how COVID-19 is affecting individuals in a number of cognitive-related areas, including memory loss, “brain fog,” and dementia. “Many people who recover from mild or moderate COVID-19 notice slowed thinking or memory loss, and this motivated us to leverage our experi...

People with high blood pressure diagnosed before age 55 had smaller brains compared to people who had normal blood pressure, and people who developed high blood pressure in early adulthood had the greatest reduction in brain size, according to a new study analyzing data from the UK Biobank. People d...